C-reactive protein (CRP) aptamer binds to monomeric but not pentameric form of CRP
نویسندگان
چکیده
منابع مشابه
Perplexity of monocyte responses to C-reactive protein (CRP).
Thromb Haemost 2008; 99: 461–462 C-reactive protein (CRP), a member of the pentraxin family, is one of the prototypic plasma biomarkers of inflammation (1, 2). The physiological roles of CRP in the innate immune response have, however, remained elusive as it possesses both proand anti-inflammatory actions (1, 2). Inflammation is pivotal in all phases of atherosclerosis from the nascent lesion t...
متن کاملAssociation of C-reactive protein (CRP) gene polymorphisms, serum CRP levels and cervical cancer prognosis.
BACKGROUND C-reactive protein (CRP) is the prototypical biomarker of inflammation. Genetic variations within the CRP gene have been shown to be associated with alterations of CRP expression and prognosis in cancer patients. The purpose of this study was to evaluate the association between four polymorphisms of the CRP gene, CRP serum levels, clinicopathological parameters of cervical cancer and...
متن کاملThe antimicrobial properties of C-reactive protein (CRP).
C-reactive protein, CRP, is a predominant pattern-recognition receptor (PRR) in the plasma of the horseshoe crab, which recognizes lipopolysaccharide (LPS). Native CRP2 has previously been shown to exhibit agglutination activity against the polysialic capsule of Escherichia coli K1 but its role in bacterial clearance is not well characterized. In this work, the antimicrobial activity of a recom...
متن کاملRole of C Reactive Protein (CRP) in Leptin Resistance
Increased plasma levels of both leptin and C reactive protein (CRP) have been reported in a number of conditions, including obesity, and have been linked to cardiovascular pathophysiological processes and increased cardiovascular risk; interestingly these two biomarkers appear to be able to reciprocally regulate their bioavailability, through complex mechanisms that have not been completely cla...
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ژورنال
عنوان ژورنال: Analytical and Bioanalytical Chemistry
سال: 2011
ISSN: 1618-2642,1618-2650
DOI: 10.1007/s00216-011-5174-1